Adenovector-mediated hair cell regeneration is affected by promoter type

Adenovector Mediated Inflammation in Mice Liver Boosted by Hydrodynamic Injection

Background and Aims: Adenovector gene transfer induces inflammatory response that finally leads to vector removal from delivered site. The effect of hydrodynamic pre-injection on Adenovector mediated liver inflammation remained elusive. Materials and Methods: Different mice groups were pre-treated by hydrodynamic saline, dexamethasone or nothing prior to Adeno-Luciferase administration. Their s...

Root Regeneration in Pistachio Rootstock is Affected by Auxin and Polyamines

Pistacia vera cv Badami-e-riz and P.vera cv Ghazvini are the most important and popular rootstocks in Iran, which tolerate salinity and phytophthora fungi. This study was conducted to evaluate the effects of various concentrations of polyamines and IBA on root regeneration of transplanted bare- rooted ‘Badami-e-riz’ and ‘Ghazvini’ pistachio rootstocks. The mean comparison between IBA and polyam...

Bone regeneration mediated by BMP4-expressing muscle-derived stem cells is affected by delivery system.

This study investigated the delivery of bone morphogenetic protein (BMP)4-secreting muscle-derived stem cells (MDSC-B4) capable of inducing bone formation in mice using collagen gel (CG), fibrin sealant (FS), and gelatin sponge carriers. After implanting these various cell-loaded scaffolds intramuscularly or into critical-size skull defects, we measured the extent of heterotopic ossification an...

Mammalian vestibular hair cell regeneration.

Editorial: Sensory Hair Cell Death and Regeneration

Sensory hair cells are specializedmechanosensory receptors found in vertebrate auditory, vestibular and lateral line organs that transduce vibratory and acoustic stimuli into the sensations of hearing and balance. Sensorineural hearing loss typically occurs when hair cells are damaged from infection, noise exposure, drugs (called ototoxins), and age-related decline. Unfortunately, as hair cell ...